phospho ddr2 antibody Search Results


phospho ddr2 y740 antibody  (R&D Systems Hematology)
93
R&D Systems Hematology phospho ddr2 y740 antibody
Discoidin domain receptor 2 <t>(DDR2)</t> is preferentially expressed and activated in temporomandibular joint (TMJ) articular fibrocartilage. (A) Strategy for developing Ddr2 LacZ-tagged allele mice. Mice with recombinant allele knocked into the Ddr2 locus (“knockout first” allele) were developed as described in the methods and crossed with global Cre (Sox2-Cre) mice to generate a germline Ddr2 LacZ-tagged allele (Ddr2+/LacZ). (B–G) LacZ localization in mandibular condyle (B, D, F) and knee joint (C, E, G) from 2-mo-old Ddr2+/LacZ mice. Whole mount LacZ staining (B, C). Low- (D, E) and high-magnification (F, G) histologic sections; high-magnification images are of boxed areas in D, E. (H–J) Reverse transcription quantitative real-time polymerase chain reaction detection of Ddr2 (H), Col1a1 (I), and Col2a1 (J) mRNA in TMJ and knee articular cells from 2-mo-old wild-type mice (n = 6). Values were normalized to β-actin mRNA. (K–P) Immunohistochemistry: TMJ (K, M, O, P) and knee joint (L, N). Antibodies: anti-total DDR2 (K, L, O) and anti-phospho-DDR2 <t>(Y740;</t> M, N, P). (O, P) To determine background staining, TMJs from Ddr2slie/slie mice were stained with total (O) and phosphor-DDR2 (P) antibodies. Scale bars: 0.2 mm in panel B; 0.5 mm for panel C; 40 µm for panels D, E, K–P; 20 µm for panels F, G. Arrow (O) indicates defects in condylar morphology of Ddr2slie/slie mice.
Phospho Ddr2 Y740 Antibody, supplied by R&D Systems Hematology, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/phospho ddr2 y740 antibody/product/R&D Systems Hematology
Average 93 stars, based on 1 article reviews
phospho ddr2 y740 antibody - by Bioz Stars, 2026-05
93/100 stars
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phospho ddr2 antibody  (R&D Systems)
99
R&D Systems phospho ddr2 antibody
Discoidin domain receptor 2 <t>(DDR2)</t> is preferentially expressed and activated in temporomandibular joint (TMJ) articular fibrocartilage. (A) Strategy for developing Ddr2 LacZ-tagged allele mice. Mice with recombinant allele knocked into the Ddr2 locus (“knockout first” allele) were developed as described in the methods and crossed with global Cre (Sox2-Cre) mice to generate a germline Ddr2 LacZ-tagged allele (Ddr2+/LacZ). (B–G) LacZ localization in mandibular condyle (B, D, F) and knee joint (C, E, G) from 2-mo-old Ddr2+/LacZ mice. Whole mount LacZ staining (B, C). Low- (D, E) and high-magnification (F, G) histologic sections; high-magnification images are of boxed areas in D, E. (H–J) Reverse transcription quantitative real-time polymerase chain reaction detection of Ddr2 (H), Col1a1 (I), and Col2a1 (J) mRNA in TMJ and knee articular cells from 2-mo-old wild-type mice (n = 6). Values were normalized to β-actin mRNA. (K–P) Immunohistochemistry: TMJ (K, M, O, P) and knee joint (L, N). Antibodies: anti-total DDR2 (K, L, O) and anti-phospho-DDR2 <t>(Y740;</t> M, N, P). (O, P) To determine background staining, TMJs from Ddr2slie/slie mice were stained with total (O) and phosphor-DDR2 (P) antibodies. Scale bars: 0.2 mm in panel B; 0.5 mm for panel C; 40 µm for panels D, E, K–P; 20 µm for panels F, G. Arrow (O) indicates defects in condylar morphology of Ddr2slie/slie mice.
Phospho Ddr2 Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/phospho ddr2 antibody/product/R&D Systems
Average 99 stars, based on 1 article reviews
phospho ddr2 antibody - by Bioz Stars, 2026-05
99/100 stars
  Buy from Supplier
human phospho ddr2 y740 antibody  (R&D Systems)
N/A
The Human Phospho DDR2 Y740 Antibody from R D Systems is a rabbit monoclonal antibody to DDR2 This antibody reacts with human The Human Phospho DDR2 Y740 Antibody has been validated for the following applications
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Image Search Results


Discoidin domain receptor 2 (DDR2) is preferentially expressed and activated in temporomandibular joint (TMJ) articular fibrocartilage. (A) Strategy for developing Ddr2 LacZ-tagged allele mice. Mice with recombinant allele knocked into the Ddr2 locus (“knockout first” allele) were developed as described in the methods and crossed with global Cre (Sox2-Cre) mice to generate a germline Ddr2 LacZ-tagged allele (Ddr2+/LacZ). (B–G) LacZ localization in mandibular condyle (B, D, F) and knee joint (C, E, G) from 2-mo-old Ddr2+/LacZ mice. Whole mount LacZ staining (B, C). Low- (D, E) and high-magnification (F, G) histologic sections; high-magnification images are of boxed areas in D, E. (H–J) Reverse transcription quantitative real-time polymerase chain reaction detection of Ddr2 (H), Col1a1 (I), and Col2a1 (J) mRNA in TMJ and knee articular cells from 2-mo-old wild-type mice (n = 6). Values were normalized to β-actin mRNA. (K–P) Immunohistochemistry: TMJ (K, M, O, P) and knee joint (L, N). Antibodies: anti-total DDR2 (K, L, O) and anti-phospho-DDR2 (Y740; M, N, P). (O, P) To determine background staining, TMJs from Ddr2slie/slie mice were stained with total (O) and phosphor-DDR2 (P) antibodies. Scale bars: 0.2 mm in panel B; 0.5 mm for panel C; 40 µm for panels D, E, K–P; 20 µm for panels F, G. Arrow (O) indicates defects in condylar morphology of Ddr2slie/slie mice.

Journal: Journal of Dental Research

Article Title: Selective Role of Discoidin Domain Receptor 2 in Murine Temporomandibular Joint Development and Aging

doi: 10.1177/0022034517738190

Figure Lengend Snippet: Discoidin domain receptor 2 (DDR2) is preferentially expressed and activated in temporomandibular joint (TMJ) articular fibrocartilage. (A) Strategy for developing Ddr2 LacZ-tagged allele mice. Mice with recombinant allele knocked into the Ddr2 locus (“knockout first” allele) were developed as described in the methods and crossed with global Cre (Sox2-Cre) mice to generate a germline Ddr2 LacZ-tagged allele (Ddr2+/LacZ). (B–G) LacZ localization in mandibular condyle (B, D, F) and knee joint (C, E, G) from 2-mo-old Ddr2+/LacZ mice. Whole mount LacZ staining (B, C). Low- (D, E) and high-magnification (F, G) histologic sections; high-magnification images are of boxed areas in D, E. (H–J) Reverse transcription quantitative real-time polymerase chain reaction detection of Ddr2 (H), Col1a1 (I), and Col2a1 (J) mRNA in TMJ and knee articular cells from 2-mo-old wild-type mice (n = 6). Values were normalized to β-actin mRNA. (K–P) Immunohistochemistry: TMJ (K, M, O, P) and knee joint (L, N). Antibodies: anti-total DDR2 (K, L, O) and anti-phospho-DDR2 (Y740; M, N, P). (O, P) To determine background staining, TMJs from Ddr2slie/slie mice were stained with total (O) and phosphor-DDR2 (P) antibodies. Scale bars: 0.2 mm in panel B; 0.5 mm for panel C; 40 µm for panels D, E, K–P; 20 µm for panels F, G. Arrow (O) indicates defects in condylar morphology of Ddr2slie/slie mice.

Article Snippet: Sections were incubated with total DDR2 antibody (ab5520; Abcam) or phospho-DDR2 (Y740) antibody (MAB25382; R&D).

Techniques: Recombinant, Knock-Out, Staining, Reverse Transcription, Real-time Polymerase Chain Reaction, Immunohistochemistry